Open access
Sep 2026
Diagnostic Biomarkers and Metabolic Mechanisms of Polymyxin B-Induced Acute Kidney Injury
Background/Objectives: The clinical utility of polymyxin B (PB), a critical last–line antibiotic for multidrug–resistant Gram–negative infections, is severely compromised by acute kidney injury (AKI). However, the lack of specific diagnostic biomarkers and the incomplete understanding of pathogenic mechanisms pose subs...
Si-Rui Zhao, Wei Qin, Zi-Rui Zhao et al.
· Antibiotics · 0 citations