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Peng Shi

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Open access Aug 2026

Mesenchymal Stromal Cell‐Based Cell–Drug Conjugates for the Treatment of Acute Liver Failure

ABSTRACT Acute liver failure (ALF) is a life‐threatening syndrome characterized by severe inflammatory injury and high mortality. Mesenchymal stromal cells (MSCs) hold therapeutic promise for ALF because of their immunomodulatory and tissue‐repair capacities. However, in the ALF inflammatory microenvironment, character...

Tenghui Ye, Jiamin Wu, Zixin Wu et al. · 0 citations
Aug 2026

Caged Glycan-Antibody Conjugates for Tumor-Selective Activation of Lysosome-Targeting Chimeras.

A chemically activatable LYTAC platform that leverages tumor microenvironment-specific cues to achieve precise and safe protein degradation in vivo is reported, significantly enhancing the safety and therapeutic window of lysosome-targeted degradation strategies in cancer therapy.

Mohan Chen, Yi-Cun Li, Xue-Ting Wei et al. · 0 citations

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