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Author

Peng Sun

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Open access Sep 2026

Basal-like Phenotype Identifies Immunotherapy-Responsive Subset of HR+/HER2- Breast Cancer with Aggressive Clinical Behavior

Simple Summary HR+/HER2- breast cancer represents 70% of all breast cancers but has shown limited benefit from immunotherapy, with pathological complete response (pCR) rates of only 24–30% compared to 58–66% in triple-negative breast cancer (TNBC). This resistance has been considered an immutable biological characteris...

Fang-Yu He, Yu Wu, Lu Pan et al. · 0 citations
Review Open access Aug 2026

The roles of chromatin remodeling and 3D genome organization in cancers: from mechanistic insights to emerging treatment options

A comprehensive synthesis of the mechanisms and functional roles of classical chromatin remodelers within both physiological and neoplastic contexts is provided and a hierarchical framework that distinguishes between 'first-level' and 'higher-order' chromatin remodeling is proposed.

Chu-Qiao Luo, Ning-Lin Xia, Shin-Yee Hui et al. · 0 citations

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