Review
Open access
Sep 2026
Tumour-associated dsRNA accumulation and innate immune activation: mechanistic basis and therapeutic strategies
This Review examines critical-target and cumulative-burden models, methods for ligand identification, biomarker-guided patient selection and therapeutic strategies based on viral mimicry, ADAR1 targeting, engineered dsRNA agonists, and delivery platforms.
Shao-Ping Li, Yan-Fei Huo, Hang-Wei Fa et al.
· EBioMedicine · 0 citations