Open access
Aug 2026
Integrated Transcriptomic and DNA Methylation Analysis Reveals ITGB2-Mediated Immune Dysregulation in Polycystic Ovary Syndrome and Its Modulation by Rutin.
ITGB2 is associated with inflammatory responses in granulosa cells and may contribute to PCOS-related immune dysregulation via NF-κB activation and Rutin attenuates these inflammatory responses, supporting a potential involvement of the ITGB2/NF-κB axis as a therapeutic target.
Peng Yi, Ying-Ying Cao, Yan-Ru Zhou et al.
· Reproductive Sciences · 0 citations