Carboxylesterase-Activated NIR-II Thioxanthene Probe for Enhanced Photoacoustic Imaging and Type I Phototherapy of Hepatocellular Carcinoma
To address the bottlenecks of poor tumor specificity and compromised photodynamic therapeutic efficacy caused by the hypoxic microenvironment in solid hepatocellular carcinoma (HCC), a water-soluble NIR-II thioxanthene probe with galactose targeting and carboxylesterase (CE)-activatable property was synthesized via e...