Jul 2026
MEX3B as a Potent Regulator of Inflammasome Signaling 2267250
Deletion of MEX3B inhibited caspase-4 and gasdermin D activation, pyroptosis, and secretion of inflammasome-dependent inflammatory cytokines in human cell lines and murine primary macrophages and suggested that MEX3B is a pan-inflammasome regulator targeting inflammatory caspases.
Penghua Wang, Jason G. Cahoon, Duomeng Yang et al.
· Journal of Immunology · 0 citations