AI Networking Cookbook: Practical recipes for AI-assisted network automation and development
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Mitochondrial metabolism and epigenetic crosstalk drive SASP
It is shown that mitochondrial metabolism provides a second layer of control that enables execution of the inflammatory programme, and a mechanism that selectively controls the inflammatory output of senescent cells is revealed.
High-Specificity Detection of Chromosomal Mosaicism Reveals Cell-Type-Specific Genomic Alteration Patterns in Aging Tissues
Mosaic chromosomal alterations (mCAs) increase with age and are associated with multiple diseases, yet the cell types and states that harbor these alterations remain largely unknown. Because mCAs arise in individual cells prior to clonal expansion, they are typically rare and obscured in bulk data. We develop CHASM, a...