Extending Small-Molecule Aptamer Discovery Principles to Protein Targets: Selection and Characterization of Green Fluorescent Protein Aptamers.
Since the advent of systematic evolution of ligands by exponential enrichment (SELEX), numerous protein-binding aptamers have been reported, yet their binding characterizations are often less developed than those of small-molecule aptamers, limiting mechanistic understanding and practical applications. Here, we establi...