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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

P. Rainsford

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2 papers indexed here

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Open access Sep 2026

Fluorinated Aliphatic Thiols in the Design of Cephalosporin Conjugates for Metallo-β-Lactamase Inhibition

Antibiotic resistance is a major global health challenge, with the rapid spread of metallo-β-lactamase (MBL)-expressing bacteria presenting a serious clinical threat. In this study, we synthesized and investigated a series of novel cephalosporin conjugates envisioned to release MBL inhibitors upon MBL-mediated hydrol...

A. Kondratieva, Philip Rainsford, Perwez Bakht et al. · 0 citations
Open access Jul 2026

Chemokine receptor activity is differentially regulated by membrane cholesterol

These findings identify cholesterol as an allosteric regulator of chemokine receptors and suggest that oxysterols may reshape inflammatory signaling by selectively modulating GPCR activity.

Fernando Salgado-Polo, J. Fernández-González, Carolina Ferrera-Mena et al. · 0 citations

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