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Author

Phillip Scott

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3 papers indexed here

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Review Sep 2026

Beyond the parasite: skin-intrinsic cytolytic circuits drive disease in cutaneous leishmaniasis and reveal targets for host-directed therapy

SUMMARY Cutaneous leishmaniasis (CL) is a globally prevalent parasitic disease in which tissue pathology often arises primarily from immune-mediated damage rather than uncontrolled parasite replication. Despite effective Th1 responses and the production of IFN-γ, lesions often fail to resolve, highlighting an uncouplin...

Fernanda O. Novais, Phillip Scott · 0 citations
Open access Sep 2026

IL-1α protects intestinal barrier in murine visceral leishmaniasis

The role of IL-1α acts as a key regulator of gut barrier integrity in VL and indirectly restrains systemic IFNγ-driven inflammation, highlighting IL-1α-dependent intestinal protection as an overlooked component of VL pathogenesis.

L. A. Sacramento, P. A. Sampaio, Gabriela Castilho Martins et al. · 0 citations
#software testing Open access Aug 2026

Volatile Organic Compounds as In Vitro Biomarkers of Leishmania major

The in vitro VOC profile of Leishmania major represents a metabolic fingerprint of parasite activity and highlights candidate biomarkers with diagnostic potential and support further investigation of VOC-based tools for automated culture detection and noninvasive diagnosis in resource-limited settings.

Alex Green, A. Zabala, Phillip Scott et al. · 0 citations

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