Pierangelo Veltri

FibrilNet maps conserved and tissue-specific molecular environments across systemic amyloidoses

Interpretable Classification of Missense Variants Using ESM2 Embeddings and UMAP

Missense variants can alter protein stability, conformation, activity, or expression, yet their clinical interpretation remains challenging, particularly for variants of uncertain significance. Protein language models provide sequence derived representations that capture evolutionary and biophysical constraints, but...

3D CT-to-PET Translation via Latent Brownian Bridge Diffusion

Computed tomography (CT) and positron emission tomography (PET) provide complementary anatomical and functional information for cancer diagnosis and treatment planning. However, the widespread use of PET is limited by high radiation exposure, elevated costs, and restricted availability. To address these limitations, de...