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Piercarlo Del Console

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Open access Aug 2026

Adipocyte-derived estrogen signaling influences TROP2 expression in ERα-positive breast cancer

Background Obesity-associated alterations in the tumor microenvironment (TME) modulate breast cancer (BC) progression. In obese individuals, adipocytes, the predominant stromal component of breast tissue, display an altered endocrine and inflammatory profile, leading to increased secretion of hormones, adipokines, and...

L. Gelsomino, Linda Manna, Vittoria Marchio et al. · 0 citations

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