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Author

Pijun Su

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Aug 2026

An inherent T cell-activating mRNA delivery carrier for in vivo CAR T generation.

An inherent T cell-activating polymer-lipid nanoparticle that enables ligand-free, efficient mRNA transfection and activation of T cells in vivo, and provides a clinically translatable approach for in vivo CAR T cell generation.

Qiannan Cao, Yingli Yao, Wenming Zheng et al. · 3 citations
Review Jul 2026

Polymeric Delivery Vehicles for Nucleic Acid Vaccines: Design Strategies and Biological Barriers.

This review systematically dissects how functional polymer engineering-including interfacial shielding, targeted ligand modification, membrane perturbation, and stimuli-responsive disassembly-facilitates systemic circulation, antigen-presenting cell uptake, endosomal escape, and intracellular cargo release.

Pijun Su, Hui-Lin Yuan, Kang-Xin Zhang et al. · 0 citations

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