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Meta-analysis Sep 2026

Stage-Dependent Cognitive Effects of a Multinutrient Intervention in Alzheimer's Disease: A Stage-Stratified Meta-Analysis.

A specific multinutrient intervention provides precursors and cofactors for synaptic membrane synthesis. Randomized trials across the Alzheimer's disease (AD) continuum have reported mixed findings. We conducted a systematic review and stage-stratified meta-analysis of randomized, placebo-controlled trials. MEDLINE, Em...

Pei-Ying Han, Ping Dong, Yu-Kun Zhou et al. · 0 citations
Open access Oct 2026

Aebp1 drives a ceramide-gated Calhm2 calcium influx that injures podocytes in diabetic kidney disease.

INTRODUCTION Podocyte injury is a critical determinant of diabetic kidney disease (DKD) and other proteinuric nephropathies; however, the mechanisms linking lipotoxicity to cytoskeletal disruption remain unclear. OBJECTIVES This study aimed to identify a central regulator linking lipotoxicity to podocyte injury, deci...

Ai-Ping Duan, Yu-Cui Jiang, Xia Wang et al. · 0 citations

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