AI Networking Cookbook: Practical recipes for AI-assisted network automation and development
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Cryo-electron microscopy structures of the human AP-1 complex bound to a cargo containing tandem sorting motifs reveal that a single cargo molecule bearing tandem motifs can bridge two neighboring AP-1 complexes through a previously unrecognized μ1-σ1 inter-complex interface, thereby promoting adaptor oligomerization.
An AMBRA1-RMC1-HUWE1 signaling axis that directs HUWE1-mediated ubiquitination to mitochondria to regulate neural development is identified and mitochondrial quality-control enhancement as a potential therapeutic strategy is suggested.
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