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Ping-Ping Guo

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Open access Sep 2026

Berberine targets the PI3Kα LYS672 site to suppress the PI3K/Akt/NF-κB axis and modulate microglial functional states after intracerebral hemorrhage.

Microglia-driven neuroinflammation contributes to secondary injury after intracerebral hemorrhage (ICH). Modulating microglial functional states represents a promising therapeutic strategy. Berberine (BBR) has neuroprotective effects, but its role in ICH remains unclear. This study investigated whether BBR alleviates I...

Qing-Li Wang, Xue-Long Liu, Yang Liu et al. · 0 citations

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