Sep 2026
TREM1/DAP12-mediated neuron-microglia crosstalk in ischemic stroke: Huangxiong formula reduces Neuroinflammation and neuronal Pyroptosis.
Microglial TREM1 represents a key therapeutic target, supporting the clinical application of HXF for ischemic stroke, and HXF alleviates neuroinflammation and neuronal pyroptosis by inhibiting microglial M1 polarization through the TREM1/DAP12 pathway.
Ping-Ping Zhang, Wen-Hui Xia, Yue-Ting Huang et al.
· Experimental Neurology · 0 citations