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Open access Aug 2026

Elevated wzc Mutation Frequency Promotes Carbapenem Resistance Evolution in Hypervirulent Klebsiella pneumoniae ST23.

AbstractThe worldwide expansion of carbapenemase-producing hypervirulent K. pneumoniae (CP-hvKP) raises serious concerns about potentially untreatable invasive infections. ST23, an archetypal hvKP clone, has been highlighted due to the rising prevalence of carbapenem resistance largely driven by horizontal plasmid tran...

Tao Chen, Xue-Ting Wang, Luying Xiong et al. · 0 citations
Open access Sep 2026

GM000287 is a conserved determinant of serum resistance and virulence in Klebsiella pneumoniae

Klebsiella pneumoniae (Kp) is an opportunistic Gram-negative pathogen responsible for severe community- and healthcare-associated infections. Resistance to complement-mediated killing is an important determinant of Kp survival in human serum, yet mechanisms beyond capsular polysaccharide-mediated protection remain inco...

Xiao-Min Lin, Jun-Jun Jia, Zi-Lin Zhuang et al. · 0 citations

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