Mechanistic insights into sucralose immunotoxicology: Dose-related modulation of the gut-immune axis in food allergy.
Sucralose is a widely consumed non-caloric sweetener, but its immunotoxicological effects remain poorly defined. Integrated in vitro and in vivo methods were utilized to investigate its immunotoxicological profile. In vitro, sucralose suppressed dendritic cell maturation and IL-6 secretion, promoted the differentiation...