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Review Open access Sep 2026

Clockophagy in Alzheimer’s Disease: An Emerging Hypothesis Linking Circadian Dysfunction to Ferroptotic Vulnerability

Alzheimer’s disease (AD) is frequently associated with sleep disturbances and circadian dysfunction, which may precede or accompany clinical manifestations and have been associated with amyloid-β (Aβ) pathology, tau abnormalities, oxidative stress, lipid peroxidation, and neuronal vulnerability. Increasing evidence sug...

J. Mao, Yu-Dan Zhang, Ping Wang et al. · 0 citations
Sep 2026

Du-Shu-Wan alleviates Tau protein phosphorylation in Alzheimer's disease by regulating MAPK/JNK signaling pathway.

ETHNOPHARMACOLOGICAL RELEVANCE Alzheimer's disease (AD) is one of the leading causes of cognitive impairment and dementia among the elderly and has become an urgent public health challenge due to population ageing. Du-Shu-Wan (DSW) is an ancient Chinese herbal medicine that aims to enhance memory and soothe the spirit,...

Shang-Zhi Liu, Li-Song Ren, Ling Liu et al. · 0 citations

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