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Sep 2026

Biosynthesis of Active Ginsenoside Aglycone Analogues Using Two Oxidases Mined from Mucor spinosus.

The pharmacological activity of protopanaxadiol (PPD) can be enhanced by oxidative modification. Compared with chemical synthesis and biotransformation, synthetic biology offers a more efficient and eco-friendly approach for modifying PPD. In this study, we identified two oxidases from Mucor spinosus. MsSDR3 oxidizes C...

Yu Peng, Xue-Man Lin, Yu-Han An et al. · 0 citations
Open access Aug 2026

Chromosome-scale genome assembly of Artabotrys hexapetalus provides insights into its evolution and terpenoid biosynthesis

Artabotrys hexapetalus is used as traditional Chinese medicine for the treatment of malaria. Its antimalarial activity has been shown to be the result of the sesquiterpene designated as yingzhaosu A (YZSA), which mainly occurs in the roots of A. hexapetalus. Despite its medicinal significance, the genetic basis and mol...

Zhenxiang Cui, Dan Ye, Yun-Bao Liu et al. · 0 citations

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