Author

Po-Chun Chu

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Open access Sep 2026

GCaMP fiber photometry reveals mechanistic insights into focused ultrasound neuromodulation in acute seizures

Generalized seizures represent a major clinical challenge in epilepsy, often resistant to pharmacological treatment and associated with significant morbidity. While low-intensity focused ultrasound (FUS) has emerged as a promising noninvasive neuromodulation strategy to suppress epileptiform activity, the underlying ca...

Chen-Syuan Huang, Yi-Chun Yeh, Po-Chun Chu et al. · npj Acoustics · 0 citations

Open access Aug 2026

Low-intensity focused ultrasound neuromodulation for drug-resistant epilepsy: A randomized, sham-controlled crossover trial.

Although the primary crossover analysis did not demonstrate a statistically significant antiseizure effect, delayed seizure reduction during the extended follow-up suggests potential sustained neuromodulatory effects.

Chien-Chen Chou, Yen-Cheng Shih, Yi-Hsiu Chen et al. · Epilepsia · 0 citations