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Pradeep Punnakkal

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Open access Aug 2026

Network Topology reveals disrupted AMPA receptor stabilization leads to an impaired LTD in epileptic synapses

The cross-validation with patient transcriptomic data, demonstrated that the epileptic synapse undergoes a pathological shift and the upregulation of the auxiliary proteins functionally overpowers the established LTD machinery and prevents LTD consolidation.

Pacheriyil Meghna, S. Kateriya, Pradeep Punnakkal · 0 citations

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