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Prakash T. Parvatkar

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Sep 2026

Synthetic Studies toward Anguidine: Assembly of the Tricyclic Ether Scaffold

Anguidine, a type A trichothecene (TCN) isolated from Fusarium graminearum, features a highly functionalized 6/6/5 tricyclic scaffold incorporating a central six-membered ether ring and a C12–C13 epoxide. Its pronounced bioactivity and structural complexity render it a challenging synthetic target. Herein, we describe...

Ying-Zhao Zhao, F. Fronczek, Prakash T. Parvatkar et al. · 0 citations
Review Open access Aug 2026

Cyclic Thiosulfinates: Synthesis and Applications in Chemical Biology and Materials Science

Cyclic thiosulfinates (CTs) constitute a distinct class of organosulfur compounds characterized by a polarized ─S(═O)─S─ motif and inherent ring strain, which together dictate their unique reactivity toward thiols. Recent advances in synthetic methodologies, particularly the controlled oxidation of cyclic disulfides, h...

Benjamin Liebson, Jeffrey N. Agar, Roman Manetsch et al. · 0 citations

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