Open access
Sep 2026
MAVS maintains mitochondrial import competence and also limits RNA virus replication independently of interferon signaling
ABSTRACT Intrinsic, cell-autonomous antiviral defenses can restrict infection without involving paracrine interferon (IFN) programs. Previous studies have demonstrated the importance of intact mitochondrial homeostasis in antiviral immunity. Mitochondrial antiviral signaling (MAVS) protein is a critical adaptor molecul...
Vishal Sah, Poojitha Sai Potharaju, Karthika S. Nair et al.
· mBio · 0 citations