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The clinical applications of phytochemicals are limited due to challenges such as poor tissue distribution, low solubility in bodily fluids, low absorption, off-target toxicity, and low efficacy. Advances in nanomedicine have offered opportunities to overcome these limitations by incorporating phytochemicals into vario...
Microplastic (MP; MPs) and nanoplastic (NP; NPs) pollution poses a growing threat to global health. Their small size and large surface area facilitate ingestion, accumulation, and interactions with biological systems, leading to toxicity through oxidative stress, inflammation, mitochondrial dysfunction, and cell death....
Skin cancer therapy continues to face challenges in achieving selective tumour targeting while limiting damage to healthy tissue. Gold nanoparticles (AuNPs) and silver nanoparticles (AgNPs) have emerged as versatile platforms for skin cancer treatment, but their therapeutic behaviour is strongly influenced by the nano-...
Key barriers to clinical translation remain, including poor scalability and reproducibility of nanomaterials, patient variability in plaque biology, limited long‐term safety data, and regulatory challenges for complex nanosystems remain.
Breast cancer remains one of the foremost causes of cancer‐related mortality among women worldwide, where survival outcomes are strongly dictated by the timeliness and precision of diagnosis. In this review, we present gold nanomaterial‐driven biosensors as a transformative frontier in ultrasensitive breast cancer dete...
This review critically summarizes recent advances in herbal nanoformulations, emphasizing disease-specific molecular targets, BBB-targeting strategies, comparative nanocarrier systems, pharmacokinetic optimization, intracellular trafficking, and translational challenges.
This review highlights recent progress in the design and application of stimuli-responsive MSNs for cancer therapy, with particular emphasis on mechanisms of intracellular uptake, factors influencing cellular internalization, and strategies for controlled drug release.
In preclinical studies, BMNPs often show enhanced tumor accumulation, prolonged circulation, and reduced systemic toxicity compared with uncoated nanoparticles, although reporting heterogeneity limits direct comparisons.
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