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Pratiksha Gaikwad

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Open access Sep 2026

Base‐Mediated Tandem 1,6‐Conjugate Addition/Cyclization Enabling the Synthesis of 4,5‐Disubstituted 3(2 H )‐Furanones From Haloacetoacetates and p ‐Quinone Methides

A transition‐metal‐free tandem 1,6‐conjugate addition/cyclization of haloacetoacetates with p ‐quinone methides has been developed as an efficient strategy for the synthesis of structurally diverse 4,5‐disubstituted 3(2H)‐furanones. The reaction proceeds under mild base‐mediated conditions, delivering the desired...

Vishal B. Karande, Amol T. Savekar, Nikhil A. Mandlik et al. · 0 citations

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