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AIM To develop a noninvasive dissolvable theranostics microneedle patch for simultaneous localized treatment and diagnosis of rheumatoid arthritis for reducing conventional systemic side effects. MATERIALS AND METHODS Naringenin nanoparticles were synthesized via ionic gelation using chitosan and sodium tripolyphosph...
Overall, this robust and highly sensitive LC-MS/MS method is reliable for trace-level quantification and demonstrated its applicability in pharmacokinetic, bioavailability, and formulation studies of diosgenin.
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