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Author

Prithu Mondal

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Open access Sep 2026

Enantiomer-specific modulation of GABAA receptors differentially regulates stress-induced dopamine dysregulation.

It is indicated that stereochemical and subunit-selective modulation of GABAA receptors critically determines circuit-level outcomes following stress and reinforce α5-GABAA receptors as a key target for normalizing hippocampal-driven dopamine system dysfunction associated with psychosis-relevant states.

Kayla Lilly, Prithu Mondal, James M. Cook et al. · 1 citation
Aug 2026

Benzodiazepines and GABAA receptor subtypes: Effects in open-field, elevated plus maze-discriminative avoidance task, and conditioned place preference in male mice.

The behavioral effects of the novel benzodiazepine-like compounds, HZ-166 and KRM-II-81, which show preferential efficacy for α2/3GABAA receptors, in comparison with the α1GABAA-selective compound, zolpidem, reinforce the role of α1GABAA receptors in benzodiazepine-induced sedation, cognitive impairment, and addiction...

V. A. Gundim, Hítalo C. da Silva, Roberta C. Dos Anjos Costa et al. · 0 citations

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