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Author

Q. Alqahtani

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Sep 2026

Indole-3-acetic acid attenuates doxorubicin-induced liver injury by modulating oxidative stress, inflammation, and VEGF/FLT1 and Keap1/Nrf2/HO-1 signaling.

Indole-3-acetic acid is identified as a promising adjunctive candidate for reducing hepatic adverse effects associated with DOX therapy, as evidenced by improvements in histopathological alterations, serum liver injury markers, oxidative stress parameters, inflammatory mediators, and apoptotic markers.

Iman H. Hasan, Q. Alqahtani, Samiyah Alshehri et al. · 0 citations
Open access Jul 2026

Involvement of NOD1/NF-κB/MAPK pathway in the protective effect of procyanidin B2 against methotrexate-induced nephrotoxicity

PCB2 reduced oxidative stress and inflammatory responses, indicating potential protective effects against MTX-induced kidney damage and prevented tissue injury and restored the altered parameters.

A. Al Tuwaijri, Ahlam M. Alhusaini, W. Sarawi et al. · 0 citations
Open access Aug 2026

Liposomal Nano-Curcumin Attenuates Cisplatin-Induced Hepatotoxicity in Rats with Concomitant Regulation of Wnt/β-Catenin/GSK-3β and Nrf2 Signaling

N-Cur mitigates oxidative damage and inflammation, thereby preserving hepatic function during CDDP-based chemotherapy, and demonstrates significant potential as a hepatoprotective agent when administered concomitantly with CDDP chemotherapy.

Q. Alqahtani, M. Atteya, T. Almatrafi et al. · 0 citations

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