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Open access Sep 2026

Triggering SORL1 Expression Restricts ccRCC Progression by Inducing Ubiquitination‐Mediated c‐Myc Degradation

ABSTRACT Clear cell renal cell carcinoma (ccRCC) represents one of the most prevalent malignancies worldwide, characterized by high incidence and mortality rates. It is characterized by mitochondrial dysfunction with enhanced Warburg effect. In this study, we identify the sortilin‐related receptor 1 (SORL1) as a regula...

Ke-Yi Wang, Wei Song, Q. Bai et al. · 0 citations
Open access Sep 2026

Noninvasive Preoperative Stratification of Renal Tumors for Aggressiveness and Prognosis

Accurate preoperative discrimination between indolent and aggressive renal lesions is essential for personalized risk-stratified management and improves the clinical outcomes of renal tumor patients. This study aimed to establish and externally validate a non-invasive computed tomography (CT)-derived radiomic model for...

Jing-Lai Lin, Lin-Peng Yao, Jian-Bo Gao et al. · 0 citations

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