Open access
Sep 2026
Sustained Activation of CaMKII Promotes Skeletal Muscle Contractile Dysfunction in Aging
Sarcopenia, the age‐related loss of muscle strength and mass, contributes to adverse health outcomes in older adults. Exercise engages calcium (Ca2+)‐ and redox‐dependent signaling pathways that enhance muscle performance and adaptation, whereas aging disrupts Ca2+ and redox homeostasis. CaMKII is a key transducer of b...
Michael R. Bene, Tae Chung, Elizabeth D. Luczak et al.
· Aging Cell · 0 citations