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Open access Sep 2026

Biomarker changes after surgical left atrial appendage occlusion: a substudy of LAAOS III.

BACKGROUND The Left Atrial Appendage Occlusion Study (LAAOS) III showed that surgical left atrial appendage occlusion (LAAO) reduced ischemic stroke or systemic embolism (SE) in patients with atrial fibrillation undergoing cardiac surgery. OBJECTIVES To explore whether LAAO changes levels of circulating biomarkers of...

M. Lauw, J. Eikelboom, Q. Yi et al. · 0 citations
Aug 2026

Incidence and Predictors of Extracranial Bleeding on Oral Anticoagulants for Stroke Prevention in Patients With Atrial Fibrillation: A COMBINE-AF Analysis.

Extracranial clinically relevant bleeding is common among patients with AF treated with OACs and may more accurately reflect the overall burden of bleeding than major bleeding alone, suggesting that additional unmeasured or unknown factors contribute to bleeding risk.

Deborah M. Siegal, Marc Carrier, M. Bahit et al. · 0 citations

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