This review systematically covers the molecular structure, classical functions, and complex regulatory networks of PIWIL4 in both cancerous and non-cancerous conditions and focuses on the molecular underpinnings of this duality—specifically, piRNA-guided targeting, differences in protein interaction networks, and the i...
Qi Deng, Yi Liu, Yang Qu et al.· Frontiers in Oncology· 0 citations
Critically appraising the existing evidence, this work identifies key knowledge gaps, such as the understudied sporadic EOPC subgroup and the lack of dedicated clinical trials, and proposes future research directions to inform early detection and optimize therapeutic strategies for this unique patient population.
This review establishes a comprehensive theoretical framework for understanding the role of ATP5A1 in disease pathogenesis and supports its potential utility in precision diagnostics and therapeutics.
Shu-Yin Yuan, Qi Deng, Hong-Juan Gao et al.· Frontiers in Cell and Develo...· 0 citations
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