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Open access Sep 2026

NEAT1_1-encoded microprotein PSNEAT1 drives rDNA transcription via phase separation with WRN.

Nuclear enriched abundant transcript 1 (NEAT1) has two isoforms that serve as core structural components of paraspeckles. Although the regulatory functions of NEAT1 as a noncoding RNA are well established, it has remained unclear whether the short polyadenylated isoform, NEAT1_1, encodes a functional microprotein. Here...

Xi-Wang Yang, Qi-Wei Chen, Ya Wen et al. · 0 citations
Review Open access Jul 2026

Notch receptors in breast cancer: context-dependent roles and therapeutic targeting.

How receptor-specific regulatory mechanisms shape distinct Notch1-4 signaling outputs are discussed and the context-dependent functions and molecular mechanisms of Notch receptors across tumor-cell states, BC molecular subtypes, and tumor microenvironmental components are summarized.

Mei Wang, Yue Mi, Qi-Nong Ye · 0 citations

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