Bone metastasis remains a major determinant of disability, treatment failure, and poor survival in solid tumors. It is no longer adequately explained as a late consequence of tumor spread or as a process driven only by osteoclast-mediated bone destruction. Current evidence supports a broader view in which bone metastas...
Qin-Gan Feng, Xiu-Hai Ji, Qi Sun et al.· Seminars in Oncology· 0 citations
Systemic inflammatory response syndrome (SIRS) carries high ICU morbidity, sepsis lacks standardized therapies, and stage-variable natural killer (NK) cell function in SIRS remains poorly defined due to insufficient single-cell evidence. Herein, we analyzed public LPS-induced SIRS peripheral blood single-cell RNA seq...
Hong-Ling Jia, Hang Zhao, Yan Li et al.· Clinical and Experimental Me...· 0 citations
Melanoma remains challenging due to pronounced heterogeneity, early metastasis, and dynamic treatment resistance. Conventional tissue biopsy and imaging provide essential information but are limited by invasiveness, sampling bias, and an inability to capture longitudinal tumor-immune evolution. As endogenous bio-nanoma...
Li Li, Xin Zheng, Jingrui Shi et al.· Microstructures· 0 citations
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