Grouper KCNE2 Restricts RGNNV Replication and Attenuates Virus-Induced Mitochondrial Depolarization and Apoptosis.
Groupers (Epinephelus spp.) are economically important marine aquaculture species in China; however, recurrent outbreaks of red-spotted grouper nervous necrosis virus (RGNNV) severely constrain sustainable production. RGNNV induces host-cell apoptosis through mitochondrial membrane-potential dissipation, and ion-channe...