Qian-Bing Wang

Evolution of Macrophage Function in Sepsis-Induced Cardiomyopathy: Cellular Networks from Immune Imbalance to Myocardial Injury.

Sepsis-induced cardiomyopathy (SICM) is an acute, often reversible myocardial depression driven by the host response to infection. Cardiac macrophages are central signaling hubs that integrate systemic danger signals and orchestrate myocardial dysfunction. We introduce a "Macrophage Functional Continuum" model, concept...