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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Qian Ding

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Open access Jan 2026

FAP as a Clinical Biomarker: FAP+ CAFs Orchestrate an Immunosuppressive Stem Cell Niche via the COL1A1/2‐CD44 Axis in Colon Cancer

This study demonstrates that FAP+ CAFs orchestrate a dual‐functional “immunosuppressive stem cell niche” via the COL1A1/2‐CD44 signaling axis and Targeting this FAP‐driven niche provides a promising strategy for overcoming immunotherapy resistance and improving clinical outcomes in CC.

Qian Ding, Qing-Yan Lu · 0 citations

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