Author

Qian Du

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Jul 2026

Identification of Potential Therapeutic Targets and Drugs for Depression: A Genome-Wide Druggable Mendelian Randomization and Molecular Docking Study.

34 potential druggable targets for depression were found, with SNRK, MANF, and P4HTM showing consistent importance across tissues and quercetagetin and myricetin emerged as promising candidates for depression therapy.

Ze-Hua Luo, Jiaqian Ma, Fan Wu et al. · Current Medicinal Chemistry · 0 citations

Review Open access Aug 2026

Targeting Ferroptosis in Sepsis: Therapeutic Potential and Mechanisms of Natural Products and Traditional Chinese Medicine

This review systematically evaluates diverse TCM-derived phytochemicals, elucidating their molecular mechanisms in attenuating sepsis-induced ferroptosis, and details how these natural products mitigate multi-organ injury by restoring iron homeostasis, quenching lipid peroxidation cascades, and upregulating core antiox...

Fan Wu, Changlan Gao, Xiangru Zheng et al. · Journal of Inflammation Rese... · 0 citations