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Author

Qian-Qian Li

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Open access Sep 2026

Eupatilin Alleviates Acute Myocardial Ischemia‐Reperfusion Injury in Rats via the Akt/GSK‐3β Pathway by Targeting COXs

ABSTRACT Eupatilin confers cardioprotection against myocardial ischemia‐reperfusion injury (MIRI). Cyclooxygenases (COXs) serve as key rate‐limiting enzymes for prostaglandin biosynthesis. This study investigated the effects of eupatilin on COXs. H9c2 cells subjected to oxygen‐glucose deprivation/reoxygenation (OGD/R)...

Min Guo, Qian-Qian Li, Li-Li Ji · 0 citations
Aug 2026

RUNX3 interaction with ATRAP regulates STZ-induced T1DN injury through NLRP3 inflammasome.

OBJECTIVE This study investigated whether RUNX3 regulates renal injury in diabetic nephropathy (DN) via ATRAP-dependent NOD-like receptor family pyrin domain containing 3 (NLRP3) inflammasome inhibition. METHODS Type 1 diabetic nephropathy (T1DN) was induced in wild-type and kidney-specific Runx3 conditional knockout...

Juan Zhou, Xiao-Lin Lin, Qian-Qian Li et al. · 0 citations

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