Altered gut microbiota composition and function potential in polycystic ovary syndrome: a multicohort metagenome-assembled genomes study.
BACKGROUND Polycystic ovary syndrome (PCOS) has been associated with gut microbial dysbiosis, but cross-cohort reproducibility and genome-resolved alterations remain insufficiently characterized. METHODS We integrated fecal shotgun metagenomic data from three independent PCOS cohorts comprising 169 participants. Taxo...