Astrocytic NOX2 contributes to ROS-associated mitochondrial dysfunction in cerebral ischemia-reperfusion injury: modulation by electroacupuncture.
BACKGROUND Cerebral ischemia-reperfusion injury (CIRI) causes severe neuronal damage, in which oxidative stress and mitochondrial dysfunction are major pathological events. Astrocytes are important regulators of redox homeostasis in the injured brain, yet whether astrocytic NADPH oxidase 2 (NOX2) contributes to mitocho...