Rational Design of Hemicyanine Platform for Engineering High-Contrast Activatable NIR-II Probes
Activatable NIR-II hemicyanine probes are crucial tools for high-contrast deep-tissue biomarker imaging. However, their development is constrained by an inherent dilemma: extending π-conjugation to narrow the energy gap inevitably compromises the fluorescence brightness in the activated state (dim on), while the stro...