Micron-scale lactoferrin proteinosomes potentiate immune activation and chemo-immunotherapy in breast cancer.
Efficient uptake by antigen-presenting cells (APCs) is critical for the immunostimulatory performance of protein-based adjuvants, yet soluble proteins often suffer from poor cellular internalization and transient immune activation. Here, we report a hierarchical micron-scale assembly strategy to construct lactoferrin p...