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Author

Qiansen Zhang

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Sep 2026

Disruption of cellular iron homeostasis by SRPX2-IRP1 interaction aggravates renal fibrosis in chronic kidney disease.

Findings reveal SRPX2 as a key pathogenic factor driving renal fibrosis by disrupting tubular iron homeostasis and Targeting the SRPX2-IRP1 regulatory axis presents a promising therapeutic strategy for slowing CKD progression.

Pei-Ran Yin, Lu-Miao Chen, M. Ding et al. · 0 citations

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