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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Qing-An Qi

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Sep 2026

Facile Synthesis of Polysubstituted Spiro‐Pyrazolone‐Pyrrolines via (1 + 4) Annulations of 4‐Halo Pyrazolones With 1‐Heterodienes

A facile and mild synthetic route to polysubstituted spiro‐pyrazolone–pyrrolidinones has been developed via a formal (1 + 4) cycloaddition between 4‐halopyrazolones and acyclic conjugated imines. The reactions proceed in high yields (up to 95%) with excellent regioselectivity, delivering the target spirocyclic compou...

Kai-Kai Wang, Xia-Shi Gao, Xiao-Ran Wang et al. · 0 citations

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