Author

Qing-Bo Liu

2 papers indexed here

We haven’t gathered this author’s papers yet. Follow them and we’ll fetch their work.

Not the right person? Other researchers publish under this name.

Sep 2026

Hypoxia-activated 2-nitroimidazole-brusatol carbonate prodrugs for enhanced gastric cancer therapy with reduced systemic toxicity.

Tumor hypoxia, a characteristic feature of solid tumors that induces chemoresistance, enables the rational design of tumor-selective prodrugs. Brusatol (BST), a natural quassinoid with broad-spectrum antitumor effects, faces obstacles to clinical translation due to high systemic toxicity and insufficient tumor selectiv...

Ji-Chong Li, Xue-Lan Ma, Zi-Jian Liu et al. · Bioorganic & Medicinal Chemi... · 0 citations

Jul 2026

Targeting Cys328 in the STAT3 DNA-binding domain with the germacrane-type sesquiterpene lactone SCP-7 inhibits colorectal Cancer growth in vitro and in vivo.

Findings identify SCP-7 as a novel covalent inhibitor targeting the STAT3-DBD with potent anti-CRC activity in vitro and in vivo, providing a promising lead compound for STAT3-targeted cancer therapy.

Yuan-Qing Li, Guxue Zhang, Yuhang Wang et al. · Bioorganic chemistry (Print) · 0 citations