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Sponsored Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt

Author

Qing-Chun Zhao

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3 papers indexed here

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Review Sep 2026

The efficacy of donepezil combination therapy strategies in Alzheimer's disease: A systematic review and network meta-analysis.

BackgroundAlzheimer's disease (AD) remains a therapeutic challenge, and adding other agents to donepezil may offer additional benefits.ObjectiveThis network meta-analysis aimed to compare the efficacy of donepezil-based combination therapies versus donepezil monotherapy in patients with AD.MethodsWe searched PubMed, Em...

Xin-Yue Ning, Yan Xiao, Nan Wang et al. · 0 citations
Sep 2026

Brain Penetration Optimization and Anti-neuroinflammation Evaluation of Potent 6-Methyl-7-azaindol-3-yl-quinazoline DYRK1A Inhibitors for Alzheimer’s Disease

Targeting dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A) to regulate microglia-mediated neuroinflammation represents a promising therapeutic strategy for Alzheimer’s disease (AD). To address the limited brain penetration of our earlier lead ZJCK-6-46, an intramolecular cyclization strategy was...

Huanhua Chen, Xin-Zhu Li, Si-Yuan Liu et al. · 0 citations

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